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Researchers at the Viterbi School of Engineering published a study at the beginning of April detailing their work using ...
One concern with in vivo CAR-Ts is the potential insertional mutagenesis of the lentiviral DNA payload, causing secondary ...
Dr. Laura Finn brings new treatment options to Louisiana using genetically altered cells to treat blood cancer patients. Here ...
Recent innovations include engineering CAR T-cells to overcome the immunosuppressive tumour microenvironment and enhancing their ability to infiltrate solid tumours.
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CAR-M technology: A novel approach to overcome CAR-T limitations in solid tumor treatmentResearchers in South Korea have proposed a novel cancer immunotherapy approach that could complement existing CAR-T (Chimeric Antigen Receptor T-cell) treatments. The work is published in the journal ...
The CAR T-cell therapy KYV-101 is safe, and showed preliminary signs of efficacy in patients with progressive forms of MS in ...
CAR T-cell therapy showed encouraging efficacy and good safety in newly diagnosed Ph-positive ALL,” the researchers wrote.
Nonviral CRISPR-based knock-in of chimeric antigen receptor transgenes into T cells for cell therapy
bound to Cas9-RNP, is then delivered to cells to promote precise knock-in via homology-directed repair. This method significantly enhances the precision and efficiency of CAR T cell production.
During a live event, Jack Khouri, MD, discussed options for patients with multiple myeloma after relapse and choices to ...
The Medicines and Healthcare products Regulatory Agency of the U.K. reports that it granted a conditional marketing authorization for the ...
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