Direct chemical synthesis has been adapted to make oligonucleotides of remarkable length, including an 800 nucleotide green ...

The nucleosides are rich in exposed hydroxyl and amino groups, so scientists use protecting groups to prevent unintended reactions with compounds used in DNA synthesis. Chemicals remove the protecting ...

The method was developed by Frederick Sanger in 1975, who was later awarded the Nobel Prize in chemistry ... the DNA to be sequenced serves as a template for DNA synthesis. A DNA primer is ...

Figure 1: Chemical synthesis and theories of structure ... Initial attention has focused on preventing commercial DNA synthesis companies from supplying pathogenic or otherwise dangerous sequences ...

Their team has made great strides in designing and developing an enzymatic DNA synthesis platform with exciting technical advantages over traditional chemical synthesis,” said Trey Martin, CEO of ...

Ibogaine — a psychoactive plant derivative — has attracted attention for its anti-addictive and anti-depressant properties.

Chemical synthesis methods include the cyclization of urea with β-aminoacrylonitrile or the hydrolysis of 2-amino-4,6-dichloropyrimidine. Cytosine can also be isolated from DNA or RNA through ...

Middle molecules with a molecular weight of more than 1,000 are difficult to synthesize due to multiple steps and time-consuming nature, demanding the development of a new approach that can overcome ...

Chemical biology: development of novel molecular probes for DNA sequencing analysis and disease gene discovery Medicinal chemistry: development of new imaging and therapeutic agents towards cancer and ...

This diagram depicts the chemical structure of pyrimidine ... These drugs interfere with DNA synthesis and replication, leading to the death of rapidly dividing cancer cells. Pyrimidine derivatives, ...