From synthetic biology and gene therapy to data storage and biofuel production, the demand for synthetic DNA is rising. (1) Chemicals remove the 5’-hydroxyl protecting group. The nucleosides are rich ...

More recently, complete chemical synthesis of poliovirus complementary DNA was a vivid demonstration that genetic instructions are sufficient to specify an active biological system 6.

When an unidentified respiratory disease began circulating the world in early 2020, molecular biology researchers suddenly found that their work was the world’s top story. Efforts to identify ...

IDT and Elegen partner to launch an early access program offering long, clonal gene synthesis and high-complexity genes up to ...

Enzymes, the core catalysts in life, drive critical biological processes ranging from metabolic regulation to energy conversion. Evolved over billions of years, these versatile molecular machines not ...

This diagram depicts the chemical structure of pyrimidine, a six-membered aromatic ring with two nitrogen atoms at positions 1 and 3 (highlighted in blue). The remaining positions are occupied by ...

The University of Connecticut mourns the loss of chemistry professor Ashis Basu, who died on March 13. The university put out a statement in which they expressed the impact Basu had on UConn and its ...

The chemical structure of uracil, showing its single-ring pyrimidine structure. Uracil forms hydrogen bonds with adenine in RNA, contributing to the molecule's structure and function. (Image: Public ...

Chemical biology: development of novel molecular probes for DNA sequencing analysis and disease gene discovery Medicinal chemistry: development of new imaging and therapeutic agents towards cancer and ...