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G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...
A number of cell surface and nuclear receptors mediate their actions via dimerization. While this has been well established, the dimerization of G-protein coupled receptors (GPCRs) (that ...
Dublin, May 06, 2025 (GLOBE NEWSWIRE) -- The "G-Protein Coupled Receptor (GPCR) Targeting: Technologies and Global Markets" report has been added to ResearchAndMarkets.com's offering. The global G ...
A recent study published in Engineering delves into the complex mechanisms of drug addiction, highlighting the crucial role ...
The 2012 Nobel Prize for Chemistry has been awarded to Robert Lefkowitz and Brian Kobilka for groundbreaking discoveries that reveal the inner workings of G-protein-coupled receptors. Professor David ...
HHMI’s Robert Lefkowitz shares prize with Brian Kobilka for research on G-protein coupled receptors. The Royal Swedish Academy of Sciences announced today that Robert J. Lefkowitz, a Howard Hughes ...
Androgens are hormones that control the development of male sexual characteristics ... able to show that one of the adhesion G protein- coupled receptors—GPR133—is activated by the androgenic ...