Antibodies generated this way contain mutated structures or linkers, are hard to purify, and are likely to have high immunogenicity that can cause antibody antidrug effects. Y-Biologics ...

after a few immunizations the immune system begins to produce antibodies against immune complexes already bound to the viral ...

By these arrangements, each of the two arms of the antibody includes one light chain and one heavy chain, with the variable regions at the tips of the Y arms defining antigen specificity.

Even with significant expansion in the global market for antibodies used in clinical care and research, scientists recognize that there is still untapped potential for finding new antibodies.

The Food and Drug Administration has approved more than 100 monoclonal antibodies to treat a range of diseases. Other ...