which includes cellular signaling pathways and downstream targets, cell differentiation and organismal development, responses to cell stress and nutritional requirements, and programmed cell death.

Glycolysis is an ancient metabolic activity. It consists of a set of reactions that convert glucose into energy. This central ...

Focal cortical dysplasia (FCD) type 2 is a congenital malformation of the cerebral cortex that is often associated with ...

This allows other cell-signalling proteins to influence NF-κB function and therefore serves as a mechanism to integrate their activities with the NF-κB and IKK pathway. NF-κB subunits can also ...

Focal cortical dysplasia (FCD) type 2 is a congenital malformation of the cerebral cortex that is often associated with difficult-to-treat epilepsy. In the affected areas, nerve cells and their layer ...

As well as providing energy to the cell, glycolysis also controls cell fate in early embryonic development, laying the ...

A landmark review in Nature Reviews Genetics dissects the rare and common genetic variants that shape human height. The paper ...

A research team led by the Guangzhou Institutes of Biomedicine and Health of the Chinese Academy of Sciences has constructed ...

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are ...

Previous work by the team had shown that the NOTCH signaling pathway played a central role ... is involved from the very start of the CD8 + T cell differentiation period, which lasts around ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...