When a signaling molecule joins with an appropriate receptor on a cell surface, this binding triggers a chain of events that not only carries the signal to the cell interior, but amplifies it as well.

Transmembrane signaling systems include membrane-bound cell surface receptors and molecules called ligands that bind to these receptors. In its most general use, "ligand" is a term for something ...

But the new strategy takes a different path: using cell surface receptors like CD36 to actively bring drugs inside. CD36 is a protein found abundantly on the surface of cells in the intestine ...

Influenza viruses are among the most likely triggers of future pandemics. A research team from the Helmholtz Center for Infection Research (HZI) and the Medical Center—University of Freiburg has ...

But the new strategy takes a different path: using cell surface receptors like CD36 to actively bring drugs inside. CD36 is a protein abundantly found on the surface of cells in the intestine ...

The labs of Ryan Flynn at Boston Children’s Hospital and Konstantinos Tzelepis at the Cambridge Stem Cell Institute have found a readily druggable target on the surface of acute myeloid leukemia (AML) ...

Scientists led by Karla Satchell, Ph.D., the Anne Stewart Youmans Professor of Microbiology at Northwestern University, have ...

François and his student François Bourassa designed a theoretical mathematical model to determine how to modulate the immune response using receptors naturally present on the surface of T-cells.

Scientists from the Keck School of Medicine at University of Southern California have developed a spectral flow ...

The neonatal Fc receptor (FcRn) is a developmentally regulated ... There, it binds FcRn and is transported to the opposite cell surface facing the lumen, where the FcRn-bound IgG is released.

The first step of toxin activity is the recognition of a specific receptor on the target cell surface. When bound to the receptor, toxins can act at the cell membrane by interfering with signal ...