Hepatitis B virus infection remains one of the leading causes of liver disease, including cirrhosis and hepatocellular carcinoma.

Then, if the virus is encountered again, that sequence produces a guide RNA that directs an enzyme called Cas9 to snip the viral DNA, preventing infection. These virus-specific sequences are ...

2 Image Credit: Gohang/Shutterstock.com In bacteria and archaea, the CRISPR-Cas9 system functions as the RNA-based adaptive immune system. This system confers resistance to viruses by introducing ...

where they help defend against viruses. The Cas9 protein is the most widely used by scientists. This protein can easily be programmed to find and bind to almost any desired target sequence ...

He studies the ways in which these viruses evade the immune system and potential therapies for these infections. Dr. Jerome and his colleagues are studying the uses of precision gene-editing tools ...

The CRISPR/Cas9 gene-editing system, based on a bacterial immune response against viruses, has been applied to human genome editing and was recently implemented in the first Food and Drug ...

CRISPR sequences—short snippets of DNA from previous viruses—guide destructive enzymes towards invading ... the enzymes to introduce cuts at specific points in the genome. Cas9, the first Cas protein ...

An interim approach involved engineering viruses that introduce new genetic ... In 2012, however, researchers developed the breakthrough CRISPR-Cas9 platform, which allows precise DNA editing.

Viruses replicate inside host cells and can ... interactome using the K1 antibody and functional studies using CRISPR-Cas9 knockout screening of these dsRBP candidates elucidate the role of ...