Hepatitis B virus infection remains one of the leading causes of liver disease, including cirrhosis and hepatocellular carcinoma.

“The study is a proof of concept that CRISPR/Cas9 can be used to destroy DNA viruses and block viral infection and disease progression,” said Yinong Yang, who studies molecular plant-microbe ...

2 Image Credit: Gohang/Shutterstock.com In bacteria and archaea, the CRISPR-Cas9 system functions as the RNA-based adaptive immune system. This system confers resistance to viruses by introducing ...

Then, if the virus is encountered again, that sequence produces a guide RNA that directs an enzyme called Cas9 to snip the viral DNA, preventing infection. These virus-specific sequences are ...

1 The key component of the CRISPR system includes the Cas9 protein, which is found in bacteria where it defends against viruses. The Cas9 protein can be easily programmed to identify and bind to ...

Building a gene editor took months. With CRISPR even high-schoolers can get hold of editing systems in the time it takes to ...

where they help defend against viruses. The Cas9 protein is the most widely used by scientists. This protein can easily be programmed to find and bind to almost any desired target sequence ...

The CRISPR/Cas9 gene-editing system, based on a bacterial immune response against viruses, has been applied to human genome editing and was recently implemented in the first Food and Drug ...

He studies the ways in which these viruses evade the immune system and potential therapies for these infections. Dr. Jerome and his colleagues are studying the uses of precision gene-editing tools ...

An interim approach involved engineering viruses that introduce new genetic ... In 2012, however, researchers developed the breakthrough CRISPR-Cas9 platform, which allows precise DNA editing.

CRISPR sequences—short snippets of DNA from previous viruses—guide destructive enzymes towards invading ... the enzymes to introduce cuts at specific points in the genome. Cas9, the first Cas protein ...

Viruses replicate inside host cells and can ... interactome using the K1 antibody and functional studies using CRISPR-Cas9 knockout screening of these dsRBP candidates elucidate the role of ...