Researchers at Karolinska Institutet, led by Dr. Helin Norberg and Dr. Erik Norberg, have identified a previously unknown ...

Another protein in cancer cells, called TBK1, can also drive EMT and appears to be triggered by AXL. TBK1 itself appears to activate the AKT family of proteins, which has three members—AKT1 ...

For cancer cells to spread, a group of cells must work together to invade new tissues. This process is called Epithelial-Mesenchymal Transition (EMT). During EMT, cancer cells change and become ...

Circulating tumor cell formation at the primary tumor site and EMT. (Top) Heterotypic interactions between the stroma and cancer cells at the primary tumor site in carcinomas lead to EMT ...

Researchers at Karolinska Institutet have identified a previously unknown mechanism that affects the ability of cancer cells ...

which helps cancer cells grow, and epithelial-mesenchymal transition (EMT), a process that allows cancer to spread. The authors suggest that combining SETDB1-blocking drugs with immunotherapy or ...

Metastatic progression is driven by the expression and stabilization of pro-metastatic proteins. This study reveals how ...

Non-coding RNAs and oxidative stress work together in various stages of cancer progression, including cancer cell growth and reproduction, cancer ...

Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related deaths worldwide.