Researchers at Karolinska Institutet, led by Dr. Helin Norberg and Dr. Erik Norberg, have identified a previously unknown ...

The epithelial–mesenchymal transition (EMT) is a cellular transdifferentiation program that enables epithelial cancer cells to acquire traits of high-grade malignancy, notably invasive and ...

For cancer cells to spread, a group of cells must work together to invade new tissues. This process is called Epithelial-Mesenchymal Transition (EMT). During EMT, cancer cells change and become ...

Another protein in cancer cells, called TBK1, can also drive EMT and appears to be triggered by AXL. TBK1 itself appears to activate the AKT family of proteins, which has three members—AKT1 ...

Researchers at Karolinska Institutet have identified a previously unknown mechanism that affects the ability of cancer cells ...

which helps cancer cells grow, and epithelial-mesenchymal transition (EMT), a process that allows cancer to spread. The authors suggest that combining SETDB1-blocking drugs with immunotherapy or ...

Non-coding RNAs and oxidative stress work together in various stages of cancer progression, including cancer cell growth and reproduction, cancer ...

Even cells experience peer pressure. Scientists have long studied the ins and outs of cancer cells to learn more about the ...

Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related deaths worldwide.

Our work provided a conceptual understanding depicting a causal role for RNA alternative splicing in EMT and breast cancer recurrence. We found that splice isoform switching of the CD44 gene must take ...