The CRISPR-Cas5-HNH/Cascade complex, which serves as an immune defense system in prokaryotes, has long been studied for its ability to protect bacteria from invading genetic materials. However ...

CRISPR-Cas systems are prokaryotic immune systems that confer resistance to foreign genetic elements such as plasmids and phages. CRISPR-Cas systems have been exploited for targeted genome editing.

Results reported in a recent Science paper provide the first experimental evidence to support the hypothesis that prokaryotes possess a defence system that might be analogous to eukaryotic RNA ...

A team of researchers at Karolinska Institutet has developed a novel tool for genetic research. The study, published in ...

View Full Profile. Learn about our Editorial Policies. Since the bacterial-origin CRISPR-Cas system rose to popularity as a genome editing tool, scientists have wondered whether other genome editors ...

CRISPR is a technology that can be used to edit genes and, as such, will likely change the world. The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell.

Learn about our Editorial Policies. We can target harmful bacteria. We can engineer beneficial bacteria. We can use CRISPR to study microbial interactions. We can use CRISPR to remove antibiotic ...

Beam Therapeutics said Monday that it used a form of CRISPR called base editing to correct, in several patients, a mutation that drives a debilitating lung condition that may affect tens of ...

They note that CRISPR systems can only be directed to ... A family of modular RNA-guided DNA-targeting systems in prokaryotes and their viruses, Science (2025). DOI: 10.1126/science.adv9789 ...

Aude Bernheim is a microbiologist studying how bacteria defend against viruses. She earned her PhD at the Pasteur Institute in Paris, researching CRISPR-Cas evolution, and completed a postdoc at the ...