CRISPR-Cas9 is not the first method available to scientists ... Another result of this research are zinc finger nucleases. These artificial enzymes consist of a sub-unit that recognizes the desired ...

zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and CRISPR/Cas9. All these technologies create double-strand breaks in DNA, which can be repaired either by ...