It’s a new way to create “bi-paternal” mice that can survive to adulthood—but human applications are still a long way off.

“It shows that CRISPR-mediated gene editing can lead to real amelioration of hearing loss in vivo.” The so-called Beethoven mouse model has the same point mutation in the mouse version of Tmc1 that in ...

No doubt 2025 will usher in many more advances in CRISPR therapies, thanks to the FDA’s new Platform Technology Designation ...

At first glance, the seven mice skittering around their cages look like other mice ... They then zeroed in on 20 genes and tinkered with them using the gene-editing tool CRISPR. Hundreds of ...

(REUTERS) British scientists are testing cutting edge gene editing techniques in mice, by inserting a jelly fish gene that makes their skin green. The research uses CRISPR-Cas9, a gene editing ...

This will allow quicker and easier gene knock-down experiments, for example, because having on-board Cas9 makes more room in vectors used to deliver the guide RNA to contain multiple instructions for ...

In new mouse models of the disease ... To fix the dysferlin mutation, Escobar uses CRISPR-Cas9, which is often described as "gene-editing scissors" and for which a Nobel Prize was awarded in ...

A minimum of 3 positive founders will be delivered. To produce CRISPR/cas9-mediated gene indels to generate knock-out mice or rats. The investigator will provide or purchase the CRISPR gRNA(s). TGEF ...

CRISPR-Cas9 genome editing exploits the CRISPR ... Here, the authors show in mice a microneedle drug delivery platform loaded with metal-organic frameworks (MOFs) and CRISPRa-UCP1 system to ...

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse ... of CRISPR-Cas9 gene editing ...