Scientists have been genetically engineering mice since the 1970s, but new technologies like CRISPR "make it a lot more efficient and easier," said Lynch. The Colossal scientists reviewed DNA ...

In new mouse models of the disease ... To fix the dysferlin mutation, Escobar uses CRISPR-Cas9, which is often described as "gene-editing scissors" and for which a Nobel Prize was awarded in ...

Enter the mouse, an animal whose genome lends itself to easy manipulation with CRISPR—a gene-editing tool developed in 2012, based on a natural process bacteria use to defend themselves in the wild.

A team of researchers at Karolinska Institutet has developed a novel tool for genetic research. The study, published in ...

Tel Aviv University researchers used CRISPR to cut the SOX2 gene from head and neck cancer cells, eliminating 50% of tumors in mice. The study, published in Advanced Science, highlights CRISPR’s ...

(Colossal Biosciences via AP) Scientists have been genetically engineering mice since the 1970s, but new technologies like CRISPR “make it a lot more efficient and easier,” said Lynch.

Thus armed, the team at Colossal began to engineer those mutations into laboratory mice using tools based on the gene-editing technology called CRISPR, which can be thought of as a pair of ...

CRISPR-Cas9 genome editing exploits the CRISPR ... system to correct the point mutation in a preclinical RP mouse model. In vivo treatment achieves genome editing and restores mice vision.