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Researchers at Karolinska Institutet have developed a technique that enables efficient delivery of therapeutic proteins and ...
(2) Researchers deliver CRISPR system components using different methods, including conjugation, transformation by heat shock or electroporation ... in it still have many challenges ahead. DNA ...
Brief electroporation appears to make T cells more receptive to new genetic material, which could speed the development of immunotherapies. Ashley started at The Scientist in 2018. Before joining the ...
jetMESSENGER ® reagent considerably outstrips Lipofectamine ™ 2000 transfection reagent in T cells, reaching more elevated GFP expression while preserving cell integrity. In B cells, it shows superior ...
“At the time, there was a growing interest in using this application for CRISPR gene ... way to make even the delivery of larger cargo more efficient. Meanwhile, electroporation equipment ...
Latest study leverages new constructs for nuclear localization signal (NLS) sequences to improve editing efficiency in human ...
Plant breeding plays a vital role in ensuring global food security by increasing crop yields, improving nutritional quality ...
Kytopen Corp., a leader in providing non-viral, continuous flow cellular engineering technologies and Aldevron, a leading global manufacturer serving organizations in the gene editing, mRNA vaccine ...
Led by Dr. Razan Masarwy and Prof. Dan Peer, the team created a CRISPR delivery system that homes in on cancer cells using antibodies. These antibodies stick to a protein called EGFR, which is ...
If RNAi is going to be viable as a therapy for organ-wide diseases such as hepatitis B or C, it will have to stick around. with the Breaking Science News daily newsletter ...
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CRISPR-Cas9 Off-Target Effects: Challenges and SolutionsThe CRISPR-Cas (Clustered Regularly Interspaced ... 2 Compared to all delivery methods, RNP electroporation exhibited higher on-target editing efficiency and lower off-target mutations.
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