CRISPR-Cas9 is a reprogrammable DNA cutting machine that is being used to edit genomes in many organisms for research purposes. Its primary component, the Cas9 enzyme (orange), cuts genomic DNA ...

Plant breeding plays a vital role in ensuring global food security by increasing crop yields, improving nutritional quality ...

Caption The anti-CRISPR protein (red on right) mimics DNA, binding in the site where the cutting enzyme Cas9 typically grips the target DNA (left) before it cuts. But the anti-CRISPR protein doesn ...

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions—but there is always room ...

Researchers using CRISPR-Cas9 gene editing tools have discovered that while this technology can enhance T cell cancer therapies, it may also lead to unintended chromosomal loss in the edited immune ...

When the CRISPR Cas9 protein is added to a cell along with a piece of guide RNA, the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a ...

Latest study leverages new constructs for nuclear localization signal (NLS) sequences to improve editing efficiency in human ...

“The authors here were also able to demonstrate that this gene editing strategy works in cells.” With the CRISPR/Cas9 system, researchers ... Lab safety rules dictate that one must tie back long hair.

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions-but there is always room for improvement.

2 Image Credit: Gohang ... and Crisflash, can predict CRISPR/Cas9 off-target effects. 5 Many of these tools are open-source online software and can be easily accessed using internet services.