CRISPR is a technology that can be used to edit genes and, as such, will likely change the world. The essence of CRISPR is simple ... defend against viruses. The Cas9 protein is the most widely ...

CRISPR-Cas9 burst onto the broader scientific scene in 2012 when a team led by Jennifer Doudna showed that it could be modified to target and cut specific segments of DNA. The CRISPR half of the ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...