CRISPR-Cas9 is the most widely used tool for genetic manipulation. The technology uses a repurposed enzyme to bind to DNA, allowing alterations at specified locations in a genome.

Please use one of the following formats to cite this article in your essay, paper or report: APA. Cuffari, Benedette. (2023, December 08). CRISPR-Cas9: Shaping the Future of Targeted Drug Development.

CRISPR gene editing means a cure for sickle cell disease is on the horizon. However, the life-changing treatment is likely to remain out of reach for most of those who could benefit.

Despite its successes, the CRISPR-Cas9 system has several limitations, including off-target cutting. Over the years, scientists have explored alternatives to Cas9, such as Cas12a for more precise ...

But until now, no one has used CRISPR-Cas9 on spiders. Researchers at the University of Bayreuth have recently successfully bred the world’s first CRISPR-Cas9-modified spider to produce red ...

Comprehensive analysis and accurate quantification of unintended large gene modifications induced by CRISPR-Cas9 gene editing. Science Advances, 2022; 8 (42) DOI: 10.1126/sciadv.abo7676; ...

For disorders caused by single genetic mutations, like Huntington’s disease and certain forms of Alzheimer’s disease, the delivery of CRISPR-Cas9 to tissues inside the body is a bottleneck.

The University of Bayreuth's Biomaterials research group has, for the first time, successfully applied the CRISPR-Cas9 gene-editing tool to spiders. Following the genetic modification, the spiders ...

Hopes and fears around gene editing While the CRISPR baby scandal tarnished the technology’s reputation, CRISPR-Cas9 and related techniques have made a major impact on biomedical research, and ...