A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

They developed a novel Tle6 gene hetero knockout male mouse model using a technique called CRISPR-Cas9 that enables the editing of genes. Their findings were published in the journal Frontiers in ...

Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, ...

(REUTERS) British scientists are testing cutting edge gene editing techniques in mice, by inserting a jelly fish gene that makes their skin green. The research uses CRISPR-Cas9, a gene editing ...

A minimum of 3 positive founders will be delivered. To produce CRISPR/cas9-mediated gene indels to generate knock-out mice or rats. The investigator will provide or purchase the CRISPR gRNA(s). TGEF ...

A new study in mice documents frequent undesirable repeats of DNA insertions ... In less than a decade since its adaptation to a genome-editing technique, CRISPR-Cas9 has been used on lab animals and ...

CRISPR-Cas9 genome editing exploits ... and validation of a Cas12a transgenic mouse model. Additionally, the authors create whole-genome Cas12a knockout libraries, and demonstrate their utility ...

which makes this gene an excellent candidate for gene editing. Researchers have previously used viral delivery of CRISPR-Cas9 components to delete the mutated exon ...

We performed genome editing of the embryos using the CRISPR-Cas9 system and electroporation to generate the Tle6 hetero knockout mice," states Kazama, explaining the main methodology used in the ...