This review will place particular emphasis on alterations of bilirubin metabolism and transport that are important in the pathogenesis of hyperbilirubinemia. Bilirubin Synthesis Although ...

The liver plays a key role in bilirubin conjugation and excretion. Any disruption in this process - whether in the production, metabolism, or excretion of bilirubin - leads to conditions such as ...

The liver plays a key role in bilirubin conjugation and excretion. Any disruption in this process—whether in the production, metabolism, or excretion of bilirubin—leads to conditions such as ...

Bilirubin is a yellowish substance in your blood. It forms after red blood cells break down and travel through your liver, gallbladder, and digestive tract before excretion. The condition of ...

Jaundice is a symptom of an underlying condition that impairs the excretion of bilirubin from the body. As the 120-day lifespan of a red blood cell comes to an end or the cell becomes damaged ...

Other interventions are designed to limit bilirubin production, enhance its metabolism and excretion, or both (Table 1). Of these interventions, metalloporphyrin inhibition of heme oxygenase ...

Truly asymptomatic elevated levels of conjugated bilirubin are less likely given that the most common causes usually generate symptoms: hepatocellular disease, impaired canalicular excretion ...