Liver, which is located in the abdomen, carries out a number of vital tasks, such as removing toxins, storing nutrients, breaking down drugs and alcohol, and creating bile, enzymes, and proteins.

We quickly realized that, unlike most conjugated bile acids, these MCBAs originated from gut microbes rather than the liver. Biology doesn’t just happen; there is likely some selective pressure ...

is a chemically modified bile acid that has already shown promising results in the treatment of liver diseases such as primary sclerosing cholangitis (PSC) and is being tested in clinical studies.

and his colleagues at first thought that DLPC would provide a useful tool in studying the function of a receptor protein – liver receptor homolog -1 or LRH-1 – that regulates the production of bile ...

Bile is a greenish-yellow liquid produced by the liver ... the muscle's function). Other symptoms of bile reflux include: Bile reflux can occur on its own but may also accompany acid reflux.

Ursodeoxycholic acid (UDCA) is widely used for the treatment ... In addition, surrogate markers of efficacy, such as standard liver function tests and liver histology, have proved to be inadequate ...