Apoptosis is a form of non-lytic programmed cell death that is important as a driver of normal development, for cell population maintenance ... SOD1 to bind and block an anti-apoptotic protein, B cell ...

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...

For this reason, this matter has recently brought a lot of attention for the development of drugs targeting ... 13 patients with a variety of relapsed B-cell NHL (five follicular, three mantle ...

Boehringer Ingelheim has joined the surge of companies entering the B-cell depletion space. But while its peers have largely ...

Review highlights how vitamin D, particularly its active form calcitriol, modulates immune responses, inflammation, and tumor ...

Recursion Pharmaceuticals RXRX announced that it has dosed the first patient in its early-stage study of investigational ...

Our immune systems weaken as we get older, making fewer cells that fight infection and help us recover from illness and injury. Scientists aren't completely sure why. They may have a better idea now, ...

“It really is very important. . . . You now have [a priority designation] that is very clearly for tissue and cell [therapies],” Beth Roxland ... potentially life-saving therapies.” The RMAT pathway ...

The results are available online to support the development of new, targeted drugs for a wide range of diseases. Cell membrane proteins ... These newly identified pathways could be leveraged ...