No doubt 2025 will usher in many more advances in CRISPR therapies, thanks to the FDA’s new Platform Technology Designation ...

It’s a new way to create “bi-paternal” mice that can survive to adulthood—but human applications are still a long way off.

Scientists in China have created mice with two biological fathers, a milestone that challenges our understanding of mammalian reproduction. While the mice exhibited significant developmental ...

(REUTERS) British scientists are testing cutting edge gene editing techniques in mice, by inserting a jelly fish gene that makes their skin green. The research uses CRISPR-Cas9, a gene editing ...

“It shows that CRISPR-mediated gene editing can lead to real amelioration ... typically during childhood. Around three weeks, mice begin to lose some of their hearing, and by eight weeks they are ...

“The treatment did not make the ALS mice normal and it is not yet a cure,” study coauthor ... “But based upon what I think is a really strong proof of concept, CRISPR-Cas9 could be a therapeutic ...

At first glance, the seven mice skittering around their cages look like other mice ... They then zeroed in on 20 genes and tinkered with them using the gene-editing tool CRISPR. Hundreds of ...

In new mouse models of the disease, they used the same process to collect cells, edit them and transplant the corrected cells back into mice ... Escobar uses CRISPR-Cas9, which is often described ...

In new mouse models of the disease, they used the same process to collect cells, edit them and transplant the corrected cells back into mice, where protein function ... To fix the dysferlin mutation, ...

A minimum of 3 positive founders will be delivered. To produce CRISPR/cas9-mediated gene indels to generate knock-out mice or rats. The investigator will provide or purchase the CRISPR gRNA(s). TGEF ...

CRISPR-Cas9 genome editing exploits the CRISPR ... Here, the authors show in mice a microneedle drug delivery platform loaded with metal-organic frameworks (MOFs) and CRISPRa-UCP1 system to ...