Cold plunges have become a fixture on wellness feeds and gym schedules. But what does science say when you strip away the ...

Physiological Roles of Autophagy How much and what parts of the cell can be eaten without causing cell death? Scientists hypothesized that the level of autophagy and the cargo specificity must be ...

However, when cells experience oxidative stress, H 2 O 2 levels can lead to autophagic failure and eventually cell death. But how? To get an answer to that and understand how autophagy can go ...

These disruptions ultimately resulted in Purkinje cell death and motor gait dysfunction, underscoring the critical role of ...

This study shows that poor oral health — particularly gum infections caused by Porphyromonas gingivalis — could make heart ...

Indeed, recent research indicates that there are other forms of programmed cell death, including an intracellular degradation process known as autophagy, which we found SAHA can trigger. Currently, we ...

Different types of programmed cell death. This picture summarizes the different pathways of programmed cell death (Note: ROS: reactive oxygen species). By unveiling the complex interactions ...

The study, published in EMBO Molecular Medicine, shows that a process called chaperone-mediated autophagy (CMA ... of the underlying causes of cancer cell spread. "Our hope is that the new ...

The Overholtzer lab studies mechanisms of nutrient sensing and cellular responses to nutrient starvation, including the nutrient recycling pathway autophagy, scavenging pathways such as ...