However, we now know that astrocytes have diverse and significant roles in glutamatergic signaling. Astrocytic glutamate transporters are the primary controllers of ambient extracellular glutamate ...

Astrocytes transport the vast majority of extracellular glutamate (especially neurotransmitter ... neurons and converted to pyruvate for energy metabolism. [1] Astrocytes have an important role ...

In some mice, they disrupted the astrocytes' ability to soak up the neurotransmitter glutamate, a chemical that excites neural activity when it is received at connections called synapses.

“The results are very clear, you know, very convincing,” says Yongjie Yang, professor of neuroscience at Tufts School of Medicine in Boston, Massachusetts, who has studied the role of astrocyte ...

Ezrin deficiency affects glutamate metabolism and alters the shape of astrocytes Histological methods and proteome analyses were able to demonstrate that the lack of Ezrin alters important cell ...

That study appeared June 26 in Neuron. An astrocyte listens in to the chemical conversation between neurons, soaking up neurotransmitters such as glutamate, the researchers showed. Astrocytes ...

“A deeper understanding of urea metabolism in reactive astrocytes may prove to be critical in understanding ... converting ornithine to putrescine rather than to its normal end product, glutamate. How ...

According to a paper in the June 17 Proceedings of the National Academy of Sciences, oligomers of the peptide may harm these structures indirectly by releasing a flood of glutamate from astrocytes.

It woke up the astrocytes the same way the genetic tweak had. It also restored normal glucose metabolism in the hippocampus, an area that's critical to memory and navigation. And once a mouse had ...

Image Credit: Kateryna Kon/Shutterstock.com The role of astrocytes in brain circuitry function, such as swift glutamate release, has been questioned due to inconsistent data and lack of direct ...

[49] Glutamate excitotoxicity ... declared they have no competing interests. Astrocytes perform critical roles in amino acid, nutrient and ion metabolism in the brain, coupling of neuronal ...