note the epitope the antibody was raised against and confirm it’s within the domain of interest. Fixation methods can alter an antigen as well, and permeabilization or antigen retrieval treatments may ...

Mapping an antibody’s epitope, where it binds a target, can now be done in three dimensions, which optimizes the selection of application-specific antibodies.

In the landmark Amgen v. Sanofi case (previously covered here), the Supreme Court affirmed that patent claims drawn to a genus of ...

we have improved the resolution of antigen arrays down to the epitope level. In this analysis, three distinct patterns of antibody reactivity were identified: (i) peptides that were differentially ...

Explore how machine learning is transforming immunology—from epitope prediction to smarter vaccine design—plus key challenges ...

Determining how to predict the antibody-antigen interactions was the biggest ... it could produce 3D structures for more than ...

Multi-epitope immunopurifications of huntingtin (HTT) from vulnerable brain regions of Huntington’s disease (HD) models ...

A technique invented by the lab, known as Electron Microscopy-Based Polyclonal Epitope Mapping ... some of the antibodies ...

U.K.-based Epsilogen has bought Boston biotech TigaTx with the aim of creating “the world’s leading pan-isotype cancer ...

The antibody 7E11 binds to the intracellular epitope ... Grimm J (2011) Targeting the internal epitope of prostate-specific membrane antigen with 89 Zr-7E11. J Nuclear Med 52(10):1608-15.