Mapping an antibody’s epitope, where it binds a target, can now be done in three dimensions, which optimizes the selection of application-specific antibodies.

note the epitope the antibody was raised against and confirm it’s within the domain of interest. Fixation methods can alter an antigen as well, and permeabilization or antigen retrieval treatments may ...

Explore how machine learning is transforming immunology—from epitope prediction to smarter vaccine design—plus key challenges ...

and epitope-optimized antibody–drug conjugates, to bispecific antibodies and chimeric antigen receptors for cell-based therapies. RubrYc’s collaboration model includes options for co-discovery ...

Multi-epitope immunopurifications of huntingtin (HTT) from vulnerable brain regions of Huntington’s disease (HD) models ...

YUMAB uses libraries of close to germline origin, but highly diverse antigen ... whole antibody-discovery process in vitro and bypassing animal immunization, YUMAB eliminates potential epitope ...

A technique invented by the lab, known as Electron Microscopy-Based Polyclonal Epitope Mapping ... some of the antibodies ...

Recombinant Monoclonal Antibodies: It is made up of identical antibody chains that target the same epitope of a certain antigen. Recombinant Multiclonal Antibodies: They are a mix of carefully ...

By cloning the variable regions of the heavy and light chains of antibodies from immunized blood donors together on a single coding region, the two produced a fusion protein with all of the antigen ...

The antibody 7E11 binds to the intracellular epitope ... Grimm J (2011) Targeting the internal epitope of prostate-specific membrane antigen with 89 Zr-7E11. J Nuclear Med 52(10):1608-15.