How can we prevent antibiotics from becoming obsolete? All that said, when it comes to antibiotic resistance, gram-negative bacteria have an edge thanks to their double membranes. The outer membrane ...

The study is a proof-of-concept that antibiotics that kill a pathogenic microbe while sparing beneficial bacteria in the gut can be developed for gram-negative infections—some of the most ...

According to the scientists, CBD analogs could constitute the first new class of antibiotics against Gram-negative bacteria that has been developed since the 1960s.

Bacteria are classified as either Gram-negative or Gram-positive based on their cell wall structure—Gram-negative bacteria have a thick layer of protection, making them difficult to kill. Most ...

Gram-negative bacteria possess an outer membrane that constitutes a formidable barrier to antibiotic penetration. This envelope, embedded with porins and other specialised channels, governs the ...

In recent decades, more antibiotics have been developed to treat Gram-positive infections, which are typically less harmful and less resistant to antibiotics than Gram-negative bacteria, Lobritz said.

Every year, more than 1 million infections occur within health care facilities in the United States. They are associated with nearly 100,000 deaths and between $28 billion and $33 billion in excess ...

BUFFALO, N.Y. — Every year, more than 1 million infections occur within health care facilities in the United States. They are associated with nearly 100,000 deaths and between $28 billion and $33 ...

Source Reference: Tingsgard S, et al "Early switch from intravenous to oral antibiotics for patients with uncomplicated gram-negative bacteremia" JAMA Netw Open 2024; DOI: 10.1001/jamanetworkopen ...

A team led by Olga Dontsova, a professor at Skoltech and Moscow State University, has demonstrated the impact of the "reverse antibiotic" on gram-negative bacteria and showed for the first time ...