The study is a proof-of-concept that antibiotics that kill a pathogenic microbe while sparing beneficial bacteria in the gut can be developed for gram-negative infections—some of the most ...

Scientists at Duke University report they have developed a synthetic antibiotic that could be effective against drug-resistant superbugs and bacteria such as Salmonella, Pseudomonas, and E. coli.

In recent decades, more antibiotics have been developed to treat Gram-positive infections, which are typically less harmful and less resistant to antibiotics than Gram-negative bacteria, Lobritz said.

A team led by Olga Dontsova, a professor at Skoltech and Moscow State University, has demonstrated the impact of the "reverse antibiotic" on gram-negative bacteria and showed for the first time ...

How can we prevent antibiotics from becoming obsolete? All that said, when it comes to antibiotic resistance, gram-negative bacteria have an edge thanks to their double membranes. The outer membrane ...

NAB741 is a non-bioactive polymyxin developed by Dr. Martti Vaara and colleagues at Northern Antibiotics designed to increase the permeability of the outer membrane of Gram-negative bacteria, thus ...

Microbiologists are on a quest to unravel a rare phenomenon involved in antibiotic resistance and how it may change our understanding of infections.

Bacteria are classified as either Gram-negative or Gram-positive based on their cell wall structure—Gram-negative bacteria have a thick layer of protection, making them difficult to kill. Most ...

IntroductionPenicillin-binding proteins (PBPs) synthesize and remodel the peptidoglycan layer of the bacterial cell wall, ...