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Novel organoid mimics all three key cell types of pancreas to offer a view of early fetal development
"Our research highlights the importance of studying human biology, as we couldn't have discovered this using animal cells." The new organoid that mimics the fetal pancreas can give scientists new ...
Phys.org29d
Nanoparticle immune therapy shows potential to halt pancreatic cancer spread
In the study, the researchers observed the appearance of killer T cells that recognize and kill KRAS-expressing pancreatic cancer cell metastases in an animal model.
Medscape23d
A Common Pancreatic Condition That Few Have Heard Of
Additionally, when functional pancreatic cells die, particularly acinar cells ... most have shown promise in preclinical animal models. But only thiazolidinediones, GLP-1 RAs, DPP-4 inhibitors ...
EurekAlert!1d
In pancreatic cancer, a race against time
CSHL Professor David Tuveson and Research Investigator Claudia Tonelli have found a way to “intercept” pancreatic cancer. By ...
Targeting FGFR2 may prevent or delay some KRAS-mutated pancreatic cancers
In a recent study, precancerous pancreatic lesions and some pancreatic ductal adenocarcinoma (PDAC) tumors harboring KRAS ...
GlobalData on MSN27d
Tumour-on-chip model could help discover pancreatic cancer therapies
The chip was integrated with PDAC spheroids, structures made of PANC-1 cells – a human pancreatic cancer cell ... thereby reducing the reliance on animal models and improving translational ...
The Scientist6y
Human Pancreas Cells Can Be Made to Produce Insulin
Jef Akst was managing editor of The Scientist, where she started as an intern in 2009 after receiving a master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses.