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Endothelial cells in tumor blood vessels respond to angiogenic factors by upregulating their rates of proliferation, migration and differentiation and lowering their rate of apoptosis, but these ...

Circadian rhythms are endogenous time-keeping mechanisms that regulate physiological processes in response to external ...

tumor invasion and neo-angiogenesis. Sorafenib is an oral multikinase inhibitor that inhibits tumor growth and proliferation by interfering with several receptor tyrosine kinases involved in the ...

Circadian rhythms are endogenous time-keeping mechanisms that regulate physiological processes in response to external light-dark cycles. These ...

Neuroendocrine tumors that start in the pancreas tend to be more aggressive and have a poor prognosis.

Circadian rhythms are endogenous time-keeping mechanisms that regulate physiological processes in response to external light-dark cycles.

The FDA approval was based on results from the CABINET study, a phase 3 pivotal trial evaluating cabozantinib compared with ...