Hence, the resulting products provided clues that the researchers could use to deduce potential codon–amino acid relationships. For example, when A and C were mixed with polynucleotide ...

Proteins are built from smaller units called amino acids, which are specified by three-nucleotide mRNA sequences called codons. Each codon represents a particular amino acid, and each codon is ...

Given that the TCG codon could efficiently instruct the ribosome to add the unconventional amino acid to a desired protein, the scientists reasoned that it might also add the new subunit to other ...

“The assignment of the genetic code has some inherent malleability, which one can change to assign existing codons to new amino acids,” said Badran. His team leveraged this by using a plug-and-play ...