The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...

The UCL School of Pharmacy has a long history of characterisation of alternative DNA structures, from the first crystal structure of a different DNA structure called a G-quadruplex, in a 2011 ...

Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA conformations—referred to as non-B DNA—have been implicated as regulators of cellular ...

The UCL School of Pharmacy has a long history of characterisation of alternative DNA structures, from the first crystal structure of a different DNA structure called a G-quadruplex, in a 2011 ...

Alternative DNA structures, such as left-handed Z-DNA, hairpin DNA, cruciform DNA, slipped-stranded DNA, parallel-stranded DNA, unpaired DNA, mirror-repeat DNA, palindrome DNA, and folded slipped ...

During DNA replication, the classic double helix can temporarily rearrange into an alternative structure known as a DNA three ...

Shankar Balasubramanian is thinking beyond DNA’s four-letter code Coinventor of next-generation sequencing has widened his focus to DNA’s large-scale structures and molecular modifications ...

In one fabrication technique—known as DNA origami—a single, long scaffold strand combines with complementary staple strands to form a nanostructure. Researchers have spent the last decade working to ...

The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a ...

Researchers, led by Penn State biologists, have comprehensively predicted the location of potential non-B DNA structures in the newly available telomere-to-telomere genomes of the great apes.