When only one allele of a gene is actively transcribed ... coupled with their chromosomal locus and tissue-specific patterns of expression, hints at their possible involvement in various inherited ...

or allele-specific methylation. The authors identified cell-type-specific patterns that provide valuable insights into how epigenetic modifications can influence gene expression and may help ...

Biased allele expression is a known genetic phenomenon ... unrelated expression phenomena that could be explained by cell to cell variation, such as cell-specific alternative splicing. He says other ...

Allele-specific insights: In 34,000 of these regions ... to uncover new regulatory mechanisms underlying imprinted gene expression and to better understand the complex interplay between genetic ...

These findings could reshape our understanding of gene expression and disease ... further computational and molecular analyses of allele-specific methylation. Its insights may lead to novel ...