The study shows that boosting mucin-type O-glycosylation in aged mice reinforces the blood-brain barrier and improves memory, ...

In mice, mucin-domain glycoproteins on blood vessels wane with age ... in mucin-domain glycoproteins contributes to peripheral immune cells infiltrating the aging brain. Loose Junctions? Normally, ...

In their latest study, published in Nature Aging on March 7, first author Lorna Jayne, Hrvatin, and colleagues show that inducing a prolonged torpor-like state in mice slows down epigenetic changes ...

Scientists suggest study findings could point to the future development of new treatments for age-related cognitive decline.

Surviving extreme conditions in nature is no easy feat. Many species of mammals rely on special adaptations called daily ...

Learn about our Editorial Policies. Now, in the new study, Sinclair and his colleagues tested whether this relocalization of chromatin modifiers is involved in aging. To do so, they developed a ...

A recent study published in the journal Nature showed that the dysregulation of the brain endothelial glycocalyx layer impairs the blood-brain barrier (BBB) in disease and aging. The BBB forms a ...