In mice, mucin-domain glycoproteins on blood vessels wane with age ... in mucin-domain glycoproteins contributes to peripheral immune cells infiltrating the aging brain. Loose Junctions? Normally, ...

The study shows that boosting mucin-type O-glycosylation in aged mice reinforces the blood-brain barrier and improves memory, ...

In their latest study, published in Nature Aging on March 7, first author Lorna Jayne, Hrvatin, and colleagues show that inducing a prolonged torpor-like state in mice slows down epigenetic changes ...

Details of this study done in mice have been published in a Science Advances paper titled, “Aging activates escape of the silent X chromosome in the female mouse hippocampus.” In it ...

Surviving extreme conditions in nature is no easy feat. Many species of mammals rely on special adaptations called daily ...

Learn about our Editorial Policies. Now, in the new study, Sinclair and his colleagues tested whether this relocalization of chromatin modifiers is involved in aging. To do so, they developed a ...

A recent study published in the journal Nature showed that the dysregulation of the brain endothelial glycocalyx layer impairs the blood-brain barrier (BBB) in disease and aging. The BBB forms a ...