Preview the May 4 matchup between the Pittsburgh Pirates and San Diego Padres with odds over/under, game spread, betting lines and more.

Luis Arraez had three run-scoring hits to lead the San Diego Padres to a 9-4 win over the host Pittsburgh Pirates on Friday ...

Aside from a rough abbreviated outing vs. the Yankees in early April, Mitch Keller has enjoyed a largely solid beginning to the season, producing four quality starts in his other five appearances.

The Pittsburgh Pirates hung around for a while but fell 9-4 to the San Diego Padres in the opening game of a series on Friday night. Adam Frazier homered to bring the Pirates within a run in the sixth ...

The Pittsburgh Pirates made three lineup changes ahead of the series finale vs. the San Diego Padres at PNC Park. Henry Davis comes in at catcher f ...

(AP Photo/Gene J. Puskar) Pittsburgh Pirates manager Derek Shelton stands in the dugout during a baseball game against the San Diego Padres in Pittsburgh, Friday, May 2, 2025. (AP Photo/Gene J. Puskar ...

PITTSBURGH — Stephen Kolek pitched 5 2/3 scoreless innings in his first major league start and combined with four relievers for the San Diego Padres ... but Adam Frazier struck out and ...

Stephen Kolek pitched 5 2/3 scoreless innings in his first major league start and combined with four relievers for the San Diego Padres ... on with one out, but Adam Frazier struck out and Hayes was ...