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The neurotransmitter acetylcholine is an essential chemical communicator, carrying impulses from neurons to skeletal muscle cells and many parts of the nervous system. Now researchers at the ...
IN spite of the simplicity of its chemical structure, details of the mode of action of acetylcholine (ACh) remain unknown. We have considered stereochemical attachment of ACh at its nicotinic and ...
Its chemical structure is similar to that of organophosphates, a common class of insecticides, which contain carbon-based groups coupled to a phosphorous atom.
X-ray crystal structures of the M1 and M4 muscarinic acetylcholine receptors, revealing differences in the orthosteric and allosteric binding sites that help to explain the subtype selectivity of ...
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