A/J mice with genetic alterations in K-ras, p53, or Ink4a/Arf were employed to investigate whether mice carrying these germline mutations would be susceptible to tobacco smoke-induced lung ...

There is some good news: the development of JAX diversity outbred (J:DO) mice. These mice are better models of human genetic diversity, have much more uniformly and widely distributed genetic ...

Previously, the researchers had demonstrated the inhibitory effect of sarunashi juice (sar-j) on mutagenesis, inflammation, and mouse skin tumorigenesis. They had identified the components of A.

arguta juice and its constituting component isoQ on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in A/J mice, and identify the possible mechanisms underlying the ...

2). Group 1 contained the fast healers, including MRL-F and LG/J mice. Strains in this group did not have an obvious slow-healing stage and closed the holes with a greater and more constant rate ...