Working with "5XFAD" mice, which genetically model Alzheimer's, Murdock and co-authors first replicated the lab's prior ...

Next, the investigators used mouse models of familial Alzheimer's disease (5xFAD) to study amyloid-beta plaque deposition. It is thought that amyloid-beta plaques disrupt normal cell function in ...

Joseph Arboleda-Velasquez of Harvard Medical School praised the results. “Ye’s group has now provided compelling evidence showing increased binding affinity of ApoE3 Christchurch for tau and its ...

2025). While this phenomenon has not yet been demonstrated in APPSwDI x NOS2 Knock-out mice, users of this model should be aware of the findings in 5xFAD mice when designing and documenting breeding ...

Honours (2010 - 2011; with Dr. Heather Schellinck): The roles of the main and accessory olfactory systems in the maternal behaviour of mice. PhD (2015 to present): Mechanisms behind weight loss seen ...