Here are score predictions for the Seahawks’ Week 6 game against the 49ers at Lumen Field from The Seattle Times sports staff.

The 49ers and the Seahawks play at 8:15 p.m. ET. Spread favorite: 49ers (-3.5) Over their last five meetings, San Francisco has totaled five wins against Seattle. The last five times the 49ers have gone up against the Seahawks, they have posted a 4-1 record against the spread. The scoring has gone over the total on two occasions.

Seattle Seahawks quarterback Geno Smith threw an interception to squander his team's solid first offensive drive, and things continued to go (mostly) downhill from there for Seattle. The San Francisco 49ers took down the Seahawks,

Through five weeks, the San Francisco 49ers have struggled to close the game. With two late-blown leads that resulted in losses, the 49ers appeared to open the door for the Seahawks for another

The San Francisco 49ers entered Thursday Night Football against division rivals the Seattle Seahawks needing a win after a stunning home loss to the Arizona Cardinals last time out.

While the San Francisco 49ers secured a much-needed win over the Seattle Seahawks on Thursday Night Football, the injury bug continued to roll in Seattle on Thursday. Multiple players, including breakout running back Jordan Mason and rookie defensive back Malik Mustapha exited the game against the Seahawks on Thursday night.

The San Francisco 49ers have released the list of inactive players for their Week 6 matchup against the Seattle Seahawks. These seven players will not suit up for the game.