It didn't take long for March Madness to deliver an upset, as No. 12 seed McNeese toppled No. 5 seed Clemson 69-67 on Thursday afternoon as first-round NCAA Tournament action began heating up. The Cowboys built a 24-point lead early in the second half and held off a late Clemson rally on to set up a showdown with No.

Madness 2025 is in full swing with four regional games Friday night. What are start times? What channel is the game on? What we know.

McNeese stunned Clemson, Arkansas squeaked by Kansas, and St. John's put together a dominant second half to set up a Pitino vs. Calipari second-round showdown. Here are the top storylines from Day 1 of the NCAA Tournament.

The Sweet 16 in the NCAA women's Basketball Tournament tips off Friday. Here is the schedule for today's games. Check back for updates throughout the day. (All times Eastern) (2) Duke vs. (3) North Carolina | 2:30 p.